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Journal Article 32

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Advances on immune-related adverse events associated with immune checkpoint inhibitors

Yong Fan, Yan Geng, Lin Shen, Zhuoli Zhang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 33-42 doi: 10.1007/s11684-019-0735-3

Abstract: activation of effector T cells, ICIs are remarkably associated with a substantial risk of immune-related adverseevents (irAEs) in almost all organs or systems.

Keywords： cancer     immunotherapy     immune checkpoint inhibitors     immune-related adverse events     review    

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surgical patients at high risk of OSAS using the Berlin Questionnaire to detect potential high risk of adverserespiratory events in post anesthesia care unit

Fei Liu, Li Liu, Fang Zheng, Xiangdong Tang, Yongxin Bao, Yunxia Zuo

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 189-195 doi: 10.1007/s11684-017-0533-8

Abstract: are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverserespiratory events in the post anesthesia care unit (PACU).Furthermore, the incidence of adverse respiratory events in the PACU was higher in patients with highAge, high risk for OSAS, and smoking were independent risk factors for the occurrence of adverse respiratoryevents in the PACU.

Keywords： obstructive sleep apnea     Berlin Questionnaire     Chinese surgical patients     adverse respiratory event    

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Multi-target combinatory strategy to overcome tumor immune escape

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 208-215 doi: 10.1007/s11684-022-0922-5

Abstract: inhibitors, and discusses the advantages of combination therapy, as well as the risk of immune-related adverseevents.

Keywords： immune checkpoints     multi-target     immune escape     immune-related adverse events     combination therapy    

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Detection of digestive malignancies and post-gastrectomy complications via gastrointestinal fluid examination

Lei Huang,Aman Xu

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 20-31 doi: 10.1007/s11684-016-0493-4

Abstract: Gastrointestinal fluid examination could also predict the adverse effects of postgastrectomy, such as

Keywords： gastrointestinal fluid     gastric carcinoma     biomarker     diagnosis     prognosis     gastrectomy     adverse events    

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Smoothing ramp events in wind farm based on dynamic programming in energy internet

Jiang LI, Guodong LIU, Shuo ZHANG

Frontiers in Energy 2018, Volume 12, Issue 4,   Pages 550-559 doi: 10.1007/s11708-018-0593-8

Abstract: When wind power is integrated into the main grid, ramp events caused by stochastic wind power fluctuationThis paper proposes a dynamic programming method in smoothing ramp events.that the dynamic programming method proposed is effective for smoothing wind power and reducing ramp events

Keywords： energy internet     wind power     ramp events     dynamic programming    

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The most influential “Top 10 Events” in carbon neutrality and climate change in 2022

Frontiers in Energy 2023, Volume 17, Issue 1,   Pages 1-4 doi: 10.1007/s11708-023-0869-5

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The Ejection and Sweep in the Wall Region of a Turbulent Boundary Layer Under Adverse Pressure Gradient

Zhang Qiang,Lu Lipeng

Strategic Study of CAE 2003, Volume 5, Issue 11,   Pages 47-50

Abstract:

The evolution of coherent structures in the wall region of a turbulent boundary layer under adversethat to the shear stress, the contribution of sweep motions is stronger than that of ejections under adversethe transport of shear-stress and kinetic energy of turbulence more strongly than the ejections under adverse

Keywords： coherent structures     turbulent boundary layer     adverse pressure gradients     direct numerical simulation    

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design of novel proton-pump inhibitors with reduced adverse effects

Xiaoyi Li, Hong Kang, Wensheng Liu, Sarita Singhal, Na Jiao, Yong Wang, Lixin Zhu, Ruixin Zhu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 277-284 doi: 10.1007/s11684-018-0630-3

Abstract: The development of new proton-pump inhibitors (PPIs) with less adverse effects by lowering the pKa valuesDrug-likeness screening was further conducted to obtain the candidates that significantly reduced the adverse

Keywords： proton-pump inhibitor     adverse effect     pharmacological mechanism     toxicological mechanism     pKa calculation    

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The effects of festivals and special events on city image design

LIU Yuan, CHEN Chong

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 2,   Pages 255-259 doi: 10.1007/s11709-007-0032-0

Abstract: On the analysis of the important roles of events and city image in the context of city marketing, thispaper suggests that holding festivals or special events is an effective approach to enhance city marketingThe positive impacts of festivals and special events, such as the identification of city image, the promotionThe negative impacts of festivals and special events are also talked about.Identity, the City Visual Identity and the City Behavior Identity concerned with festivals and special events

Keywords： Visual Identity     reversal     transmission     marketing     Behavior Identity    

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Characterization of bacterial communities during persistent fog and haze events in the Qingdao coastal

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 3, doi: 10.1007/s11783-020-1334-x

Abstract:

• Light haze had little effect on bacterial communities.

Keywords： Bacterial community     Persistent fog and haze     Particle size    

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Key uncertainty events impacting on the completion time of highway construction projects

Alireza MOGHAYEDI, Abimbola WINDAPO

Frontiers of Engineering Management 2019, Volume 6, Issue 2,   Pages 275-298 doi: 10.1007/s42524-019-0022-7

Abstract: This paper examines the uncertainty events encountered in the process of constructing highways, and evaluatesoften beset by uncertainties; and that there is a lack of appropriate evaluation of these uncertainty eventsIt emerged from the study that the uncertainty events affecting the construction time of highway projectstime differently, through a combination of the uncertainty events of the individual construction activitiessimple, reliable and accurate advanced machine learning technique to assess the impact of uncertainty events

Keywords： ANFIS     construction time     impact assessment     highway project     South Africa     uncertainty    

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An analysis of the adverse reactions of five kinds of intrauterine devices

Li Huajie

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 28-30

Abstract: device (IUD), Aimu ring (MCU), maternal music MCU375, uterine shaped ring GCU300, TCU220C and genefex of adverseThe adverse reactions of MCU375 were serious, the adverse reactions of GCU300 and MCU were followed,and the adverse reactions of TCU220c and Ji Nihuan were the lightest..

Keywords： IUD     adverse reaction     Jeanne ring    

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Adverse Geology Identification Through Mineral Anomaly Analysis During Tunneling: Methodology and Case Article

Zhenhao Xu, Tengfei Yu, Peng Lin, Shucai Li

Engineering 2023, Volume 27, Issue 8,   Pages 150-160 doi: 10.1016/j.eng.2022.09.013

Abstract: span style="font-size:10.5pt">Accurate and effective identification of adverseCurrent methods of identifying adverse geology depend on the experience of geologists and are prone toHere, we propose a method for adverse geology identification in tunnels based on mineral anomaly analysisThe proposed method provides a timely warning when a tunnel enters areas affected by adverse geologyThis method improves our ability to identify adverse geology, from qualitative to quantitative, and can

Keywords： Mineral anomaly     Adverse geology     Fault     Alteration     Anomaly threshold    

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evolution of charged and neutral nanoparticle concentrations during atmospheric new particle formation events

E. Rohan Jayaratne, Buddhi Pushpawela, Lidia Morawska

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0862-x

Abstract: Over 100 new particle formation events were studied.In 50 events, charged and neutral particles were not formed at the same time.In 42 of these events the charged particles formed before the neutral particles.Time series of nanoparticle number concentration during new particle formation (NPF) events in the urbanWe monitored 241 days during the calendar year 2012 over which NPF events were observed on 108 days.

Keywords： Charged particles     Cluster ions     Secondary particles     Environmental pollution    

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Key features of new particle formation events at background sites in China and their influence on cloud

Xiaojing SHEN,Junying SUN,Xiaoye ZHANG,Yangmei ZHANG,Lu ZHANG,Ruxia FAN

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0833-2

Abstract: mobility diameter sizes ranging from 3 to 800 nm were performed to study new particle formation (NPF) eventsThe formation rate of NPF events at these sites, as well as the condensation sink, is approximately 10Approximately 12%–17% of all NPF events with nucleated particles grow to a climate-relevant size (>50These kinds of NPF events were normally observed with higher growth rate than the other NPF cases.NPF events have also been found to have greater impact on CCN production in China at the regional scale

Keywords： New particle formation     Regional background     Cloud condensation nuclei     Growth rate     Formation rate    

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Title Author Date Type Operation

Advances on immune-related adverse events associated with immune checkpoint inhibitors

Yong Fan, Yan Geng, Lin Shen, Zhuoli Zhang

Journal Article

surgical patients at high risk of OSAS using the Berlin Questionnaire to detect potential high risk of adverserespiratory events in post anesthesia care unit

Fei Liu, Li Liu, Fang Zheng, Xiangdong Tang, Yongxin Bao, Yunxia Zuo

Journal Article

Multi-target combinatory strategy to overcome tumor immune escape

Journal Article

Detection of digestive malignancies and post-gastrectomy complications via gastrointestinal fluid examination

Lei Huang,Aman Xu

Journal Article

Smoothing ramp events in wind farm based on dynamic programming in energy internet

Jiang LI, Guodong LIU, Shuo ZHANG

Journal Article

The most influential “Top 10 Events” in carbon neutrality and climate change in 2022

Journal Article

The Ejection and Sweep in the Wall Region of a Turbulent Boundary Layer Under Adverse Pressure Gradient

Zhang Qiang,Lu Lipeng

Journal Article

design of novel proton-pump inhibitors with reduced adverse effects

Xiaoyi Li, Hong Kang, Wensheng Liu, Sarita Singhal, Na Jiao, Yong Wang, Lixin Zhu, Ruixin Zhu

Journal Article

The effects of festivals and special events on city image design

LIU Yuan, CHEN Chong

Journal Article

Characterization of bacterial communities during persistent fog and haze events in the Qingdao coastal

Journal Article

Key uncertainty events impacting on the completion time of highway construction projects

Alireza MOGHAYEDI, Abimbola WINDAPO

Journal Article

An analysis of the adverse reactions of five kinds of intrauterine devices

Li Huajie

Journal Article

Adverse Geology Identification Through Mineral Anomaly Analysis During Tunneling: Methodology and Case

Zhenhao Xu, Tengfei Yu, Peng Lin, Shucai Li

Journal Article

evolution of charged and neutral nanoparticle concentrations during atmospheric new particle formation events

E. Rohan Jayaratne, Buddhi Pushpawela, Lidia Morawska

Journal Article

Key features of new particle formation events at background sites in China and their influence on cloud

Xiaojing SHEN,Junying SUN,Xiaoye ZHANG,Yangmei ZHANG,Lu ZHANG,Ruxia FAN

Journal Article